| Titre : | HEALTH RELATED QUALITY OF LIFE TRAJECTORIES OF PATIENTS IN A MOROCCAN ACUTE MEDICAL UNIT : A LATENT CLASS GROWTH MODELING APPROACH | | Type de document : | thèse | | Auteurs : | Adnane EL KHATTATE, Auteur | | Année de publication : | 2016 | | Langues : | Français (fre) | | Mots-clés : | Acute medical unit (AMU) EQ5D Health related quality of life (HRQoL) Trajectory. | | Résumé : | Introduction:The objectives of this study were to identify and describe a set of longitudinal HRQoL trajectories of patients in an AMU,then determine factors associated with trajectory class membership of patients after acute illness.
Methods:This was a prospective cohort study conducted in an acute medical unit of Ibn-SinaUniversity-Hospital, Rabat, between June and September 2014. Patients aged≥17 years were included; those unable to complete the questionnaire were excluded. Demographic, medical-history, clinical and paraclinical characteristics were recorded at admission. EQ5D-index, EQ-VAS and survival status were collected at admission, 3, 6 and 18 months of follow-up. Latent-class-growth-analysis was applied to identify classes of HRQoL-trajectories. Association between baseline covariate and class membership were identified using polynomial-logistic-regression. Statistical analysis was carried out in STATA-14.
Results:We included 251 patients. The mean age: 55.6 ±18.9 years, women were 54.6%. In-hospital and 18 months follow-up mortality were 11.6% and 34.3%. Three trajectory classes were identified for EQ5D-Index; stably low(16.2%), stably moderate(30.6%), and high initially increasing(53.2%). The three trajectory classes of EQ-VAS were low increasing(29.7%), moderate initially increasing(48.5%) and high initially increasing(21.8%).
EQ5D-index: comparing to high initially increasing, factors associated to stably low trajectory membership were: age≥70years, ICU transit and low hemoglobinemia. EQ-VAS: comparing to high initially increasing, factors associated tolow increasing trajectory membership were: female gender, Km-hospital-residence and comorbidity.
Conclusions:We identified 3 stable HRQoL-trajectories, confirming that previous-HRQoL is more important in defining HRQoL evolution than acute illness. Elderly with low hemoglobinemia and who transited through ICU had the worst EQ5D-index. Females, with comorbidities, living far from hospital perceived an amelioration of their low EQ-VAS.
Keywords: Acute medical unit (AMU), EQ5D, Health related quality of life (HRQoL), Trajectory.
| | Numéro (Thèse ou Mémoire) : | M3712016 | | Président : | ABOUQAL.R | | Directeur : | BELAYACHI.J | | Juge : | MADANI.N | | Juge : | AHID.S |
HEALTH RELATED QUALITY OF LIFE TRAJECTORIES OF PATIENTS IN A MOROCCAN ACUTE MEDICAL UNIT : A LATENT CLASS GROWTH MODELING APPROACH [thèse] / Adnane EL KHATTATE, Auteur . - 2016. Langues : Français ( fre) | Mots-clés : | Acute medical unit (AMU) EQ5D Health related quality of life (HRQoL) Trajectory. | | Résumé : | Introduction:The objectives of this study were to identify and describe a set of longitudinal HRQoL trajectories of patients in an AMU,then determine factors associated with trajectory class membership of patients after acute illness.
Methods:This was a prospective cohort study conducted in an acute medical unit of Ibn-SinaUniversity-Hospital, Rabat, between June and September 2014. Patients aged≥17 years were included; those unable to complete the questionnaire were excluded. Demographic, medical-history, clinical and paraclinical characteristics were recorded at admission. EQ5D-index, EQ-VAS and survival status were collected at admission, 3, 6 and 18 months of follow-up. Latent-class-growth-analysis was applied to identify classes of HRQoL-trajectories. Association between baseline covariate and class membership were identified using polynomial-logistic-regression. Statistical analysis was carried out in STATA-14.
Results:We included 251 patients. The mean age: 55.6 ±18.9 years, women were 54.6%. In-hospital and 18 months follow-up mortality were 11.6% and 34.3%. Three trajectory classes were identified for EQ5D-Index; stably low(16.2%), stably moderate(30.6%), and high initially increasing(53.2%). The three trajectory classes of EQ-VAS were low increasing(29.7%), moderate initially increasing(48.5%) and high initially increasing(21.8%).
EQ5D-index: comparing to high initially increasing, factors associated to stably low trajectory membership were: age≥70years, ICU transit and low hemoglobinemia. EQ-VAS: comparing to high initially increasing, factors associated tolow increasing trajectory membership were: female gender, Km-hospital-residence and comorbidity.
Conclusions:We identified 3 stable HRQoL-trajectories, confirming that previous-HRQoL is more important in defining HRQoL evolution than acute illness. Elderly with low hemoglobinemia and who transited through ICU had the worst EQ5D-index. Females, with comorbidities, living far from hospital perceived an amelioration of their low EQ-VAS.
Keywords: Acute medical unit (AMU), EQ5D, Health related quality of life (HRQoL), Trajectory.
| | Numéro (Thèse ou Mémoire) : | M3712016 | | Président : | ABOUQAL.R | | Directeur : | BELAYACHI.J | | Juge : | MADANI.N | | Juge : | AHID.S |
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